| Customization: | Available |
|---|---|
| CAS No.: | 42464-96-0 |
| Formula: | C10h11n12 |
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Insen Supply Good Quality 5-Amino-1MQ iodide NNMTi Powder
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Product Name: |
5-Amino-1-Methyl-1-Quinolinium Iodid/NNMTi |
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Cas No.: |
42464-96-0 |
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Appearance |
Brown red powder |
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Source: |
Chemical |
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Application: |
Health supplements |
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Assay: |
98% |
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Test method: |
HPLC |
5-Amino-1-Methyl-1-Quinolinium Iodid/NNMTi is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50=1.2 μM) and selectively binds to the NNMT substrate-binding site residues. NNMTi promotes myoblast differentiation in vitro and enhances fusion and regenerative capacity of muscle stem cells (muSCs) in aged mice.
NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathway
Antioxidant and anti-inflammatory supplements to reduce free radical damage and chronic inflammation.
Neurological health support, if proven to be beneficial for cognitive function or neuroprotection, may be used in brain health supplements.
Immune support or antimicrobial ingredients, if proven to be antimicrobial, may be used in immune enhancement products.
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